Antianaerobic Activity of Sulopenem Compared to Six Other Agents

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Antianaerobic activity of sulopenem compared to six other agents.

Agar dilution MIC methodology was used to compare the activity of sulopenem with those of amoxicillin/clavulanate, ampicillin/sulbactam, piperacillin-tazobactam, imipenem, clindamycin, and metronidazole against 431 anaerobes. Overall, MIC(50)/(90) values were as follows: sulopenem, 0.25/1.0 microg/ml; amoxicillin/clavulanate, 0.5/2.0 microg/ml; ampicillin/sulbactam, 0.5/4.0 microg/ml; piperacil...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2009

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.01557-08